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This might be, at least in part, to the fact that apoptosis was the only mode of cell death that could be examined using marker proteins (caspases and their substrates) as well as electron and fluorescence microscopy when the studies were performed

Under aerobic conditions, the carbon-centred radical readily interacts with molecular oxygen to form peroxyl radicals, which react with the protonated form of superoxide (HO 2 ) and are converted to the alkyl peroxides [5,60]